Author
Royal College of Surgeons in Ireland
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
7 papers
Recent·Most cited
Pablo Quintana-Sarti, Jordan Higgins, Cristina Ruedell Reschke…·David Clifford Henshall
This study shows inhibiting miR-134 reduces single neuron and network hyperexcitability in mice with drug-resistant temporal lobe epilepsy.
Ronan Murphy, Javier Villegas-Salmerón, Amaya Sanz‐Rodriguez…·Eva Maria Jimenez-Mateos
The paper compares miRNA profiles across HT22, N2A, SH-SY5Y cell lines and primary mouse hippocampal neurons to assess their similarity to primary neurons.
Radharani Benvenutti, Danielle do Carmo Ferreira Bruno, Matheus Gallas‐Lopes…·Cristina Ruedell Reschke
This study shows that epileptogenesis disrupts the circadian clock and alters diurnal transcriptomic rhythms in the mouse hippocampus, with implications for human epilepsy.
Elizabeth Brindley, Mona Heiland, Catherine Mooney…·David Clifford Henshall
The paper identifies brain-originating microRNAs in the blood of mice with experimental epilepsy, supporting their use as biomarkers.
Gareth Morris, Elena Langa, Conor Fearon…·David Clifford Henshall
This paper demonstrates the effectiveness of antimiR-134 in reducing miR-134 levels in human brain tissue sections, supporting its potential as a treatment for pharmacoresistant epilepsy.
Cristina Ruedell Reschke, Luiz Fernando Almeida Silva, Vamshidhar R. Vangoor…·David Clifford Henshall
This study shows that systemic delivery of Ant-134, timed with BBB disruption after status epilepticus, suppresses seizures in mice with long-lasting effects.
Morten Trillingsgaard Venø, Cristina Ruedell Reschke, Gareth Morris…·David Clifford Henshall
The paper identifies functional miRNAs and their targets involved in seizure suppression in temporal lobe epilepsy using animal models and functional screens.