Gareth Morris

The paper introduces a miR-sensing plasmid system that dynamically controls ion channel expression using microRNA signals, demonstrating its ability to modulate transgene activity in neuro2A cells.

The paper identifies brain-originating microRNAs in the blood of mice with experimental epilepsy, supporting their use as biomarkers.

This study identifies miR-335-5p as a regulator of voltage-gated sodium channels, showing that its modulation can influence seizure activity in epilepsy models.

This paper demonstrates the effectiveness of antimiR-134 in reducing miR-134 levels in human brain tissue sections, supporting its potential as a treatment for pharmacoresistant epilepsy.

The paper identifies functional miRNAs and their targets involved in seizure suppression in temporal lobe epilepsy using animal models and functional screens.