Excitatory Neuron-Derived Interleukin-34 Controls Cortical Developmental Microglia Function
Benjamin A. Devlin, Dang M. Nguyen, Diogo Ribeiro, Gabriel Grullon, Madeline J. Clark, Amelie Finn, Alexis M. Ceasrine, Seneca R. Oxendine, Martha Deja, Ashka Shah, Shomik S. Ati, Anne Schaefer, Staci D. Bilbo
This study identifies IL34 as a neuron-derived cytokine that regulates microglia maturation and synapse engulfment in the developing mouse cortex.
bioRxiv · May 10, 2024 · PreprintNeuroscience