Staci D. Bilbo

This study shows that microglia regulate dopamine receptor pruning in adolescent rats, influencing social behaviors through complement-mediated engulfment, with sex-specific effects of social isolation.

This study shows maternal high-fat diet causes sex-specific microglia remodeling of serotonergic reward circuits in mice, leading to altered behavior and serotonin function.

This study shows that prenatal exposure to environmental stressors disrupts gut macrophage development and causes GI dysfunction in male offspring.

This study examines the role of microglial MyD88 signaling in voluntary ethanol consumption in mice, finding minimal effects on drinking but potential developmental context influences.

The paper investigates how an influenza A-derived immune engram influences anxiety and cytokine expression through CGRP signaling in the posterior insula.

This study shows that microglial MyD88 signaling affects ECM development and interneuron maturation in the hippocampus, with sex-specific effects on PVI density and behavior.

This study shows that preventing microglial reactivity protects against acute and progressive neurological dysfunction and motor impairments caused by alcohol abuse in mice.

The paper shows that Hofbauer cells and fetal brain microglia share transcriptional profiles and responses to maternal diet-induced obesity, suggesting Hofbauer cells as a noninvasive biomarker for fetal microglial programming.

This study identifies IL34 as a neuron-derived cytokine that regulates microglia maturation and synapse engulfment in the developing mouse cortex.

This study investigates HMGB1-induced anxiety in mice, finding sex-specific differences in microglial MyD88-dependent pathways in the medial prefrontal cortex.

This study examines how maternal diesel exposure and choline supplementation interact to affect fetal and placental immune factors, revealing region- and sex-specific effects on inflammation and microglial morphology.

The paper shows maternal high-fat diet affects placenta-brain communication differently in male and female offspring, leading to sex-specific behavioral and serotonin-related changes.

The paper shows that prenatal exposure to air pollution and maternal stress in mice causes social deficits in male offspring, which can be prevented by microbiome modulation or dopamine activation.

This study shows that male-biased social behavior deficits after early-life immune activation are linked to microglial mitochondrial dysfunction and are influenced by perinatal gonadal hormones.

This study shows that prenatal exposure to environmental toxins and stress impairs microglial function and leads to behavioral issues in male mice.

This study shows that prenatal opioid exposure reduces microglial pruning of dopamine D1 receptors in male rats, leading to increased D1R density and impaired extinction of oxycodone-conditioned place preference.

The paper uses single-cell RNA sequencing to compare fetal brain microglia and Hofbauer cells, revealing shared transcriptional programs and sex-specific differences.

This study shows that reducing tau with a degrader prevents mitochondrial fragmentation and oxidative stress in ALS models.

This study shows that morphine exposure during adolescence affects c-Fos expression differently based on age, sex, and brain region.

This study shows that neonatal immune challenge reduces social behavior in adult female mice and increases somatostatin interneurons in the ACC, independent of microglial inflammation.

This study shows microglia eliminate dopamine D1 receptors in the nucleus accumbens, influencing sex-specific social play behavior during adolescence.