Characterizing Compounds Targeting Colorectal Cancer Derived From Monastrol Using High-Through Screening of an Extensive Combinatorial Library
Alejandro Rodríguez-Martínez, Lucía Giraldo-Ruiz, Maria C. Ramos, Irene Luque, Diogo Ribeiro, Fátima Postigo-Corrales, Begoña Alburquerque-González, Silvia Montoro‐García, Ana Belén Arroyo-Rodríguez, Pablo Conesa‐Zamora, Ana María Hurtado-López, Ginés Luengo‐Gil, Horacio Pérez‐Sánchez
This paper identifies two fascin-binding compounds using a virtual screening approach combined with experimental validation, showing they inhibit CRC cell proliferation and migration.
Cancer Cell International · Sep 22, 2026Peer-reviewedCancer Biology