Proteolytic remodeling by Yme1 enables mitochondrial-derived compartment formation
Sai Sangeetha Balasubramaniam, Amy E Curtis, Jonathan R. Friedman, Adam L. Hughes
This study identifies Yme1 as a critical protease for mitochondrial-derived compartment (MDC) formation, showing its proteolytic activity enables MDC biogenesis under stress.
bioRxiv · Apr 5, 2026 · PreprintCell Biology