Author
The University of Texas Southwestern Medical CenterORCID 0000-0001-8155-2429Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Abhishek Kumar, Abigail C. Love, Keri‐Lyn Kozul…·Jonathan R. Friedman
The paper identifies ARMC1 as a repressor of mitophagy that interacts with TMEM11, BNIP3, and NIX, and shows TMEM11 antagonizes PPTC7 to protect receptors during mitophagy activation.
Sai Sangeetha Balasubramaniam, Amy E Curtis, Jonathan R. Friedman, Adam L. Hughes
This study identifies Yme1 as a critical protease for mitochondrial-derived compartment (MDC) formation, showing its proteolytic activity enables MDC biogenesis under stress.
Bingying Chen, Alfred Millett-Sikking, Seweryn Gałecki…·Reto Paul Fiolka
The paper introduces miOPM, a reconfigurable LSFM platform that enables high-resolution imaging across multiple spatial scales and refractive indices.
Alia R. Edington, Olivia M. Connor, Abigail C. Love…·Jonathan R. Friedman
This study identifies CCDC51 as a human ortholog of yeast Mdm33, showing they both regulate mitochondrial fission and are conserved in function.
Lianjie Wei, Mehmet Oguz Gok, Jordyn D. Svoboda…·Natalie M. Niemi
This paper shows that PPTC7 limits mitophagy by interacting with BNIP3 and NIX, promoting their proteasomal degradation through dynamic, proximal associations.
Madeleine Marlar-Pavey, Daniel Tapias-Gomez, Marcel Mettlen, Jonathan R. Friedman
The paper identifies METEORs, mitochondria specialized for filopodia, and shows their role in supporting cellular migration.