Cell BiologybioRxivPreprint
Protective IFIH1 variant reduces immune-mediated islet stress and dysfunction in a type 1 diabetes genetic background
Daniel Veronese-Paniagua, Cameron E Banks, Kameron Bradley…·Jeffrey R. Millman
This study shows that the IFIH1 E627* variant protects human pancreatic islets from stress-induced dysfunction by reducing immune responses and apoptosis.