Teneurin-4 switches between self-recognition and canonical Latrophilin binding to direct neuronal migration
Miguel Berbeira-Santana, Claudia Peregrina, Kosuke Okuda, Jinchuan Zhou, Maria Carrasquero, Amy V. Roberts, Anne E. Thomas, Evert Haanappel, Matthieu G. Chavent, Kamel El Omari, Lindsay A. Baker, Daniel T. Pederick, Els Pardon, Jan Steyaert, U. Valentin Nägerl, , Elena Seiradake
The paper shows how Ten4 switches between self-recognition and Latrophilin binding to guide neuronal migration through exclusive structural interactions.
bioRxiv · Sep 9, 2025 · PreprintNeuroscience