Elena Seiradake

This study identifies FLRT3-RND3 signaling as a conserved negative regulator of cortical neuron migration and folding in mice.

This study identifies LRRTM4 as a coordinator of cell migration through interactions with glypicans in developing cortex and cancer cells.

This study shows bacterial Teneurins are accessory proteins with encapsulated toxins, suggesting they were repurposed by metazoans for neuronal communication.

This study presents the cryo-EM structure of DISC1, revealing its homotetrameric architecture and its ability to bind multiple partner proteins.

The paper shows how Ten4 switches between self-recognition and Latrophilin binding to guide neuronal migration through exclusive structural interactions.

This study identifies teneurin-3 and latrophilin-2 as key molecules in forming the somatotopic map in the mouse spinal cord, showing their role in neuronal connectivity and body localization.

This paper identifies a shared interface for EphA2-ephrin-A1 cis and trans interactions, showing cis interactions inhibit trans signaling and contribute to oncogenesis.

This study determines the structure of the GPC3-Unc5D complex and shows its role in guiding neuronal and cancer cell migration.