Daniel del Toro

FLRT cell adhesion molecules counteract protocadherin-10-dependent cell segregation during cortical neuron migration

The paper identifies PCDH10 as a regulator of neuronal clustering during cortical neuron migration, showing its interaction with FLRT proteins and its role in cortical folding.

LRRTM4 controls cell migration via Glypican interactions

This study identifies LRRTM4 as a coordinator of cell migration through interactions with glypicans in developing cortex and cancer cells.

Teneurin-4 switches between self-recognition and canonical Latrophilin binding to direct neuronal migration

The paper shows how Ten4 switches between self-recognition and Latrophilin binding to guide neuronal migration through exclusive structural interactions.

A molecular basis of somatotopic map formation

This study identifies teneurin-3 and latrophilin-2 as key molecules in forming the somatotopic map in the mouse spinal cord, showing their role in neuronal connectivity and body localization.

A double hit affecting the IKZF1-IKZF2 tandem in immune cells of schizophrenic patients regulate specific symptoms

The paper shows that reduced IKZF1 and IKZF2 in immune cells of schizophrenic patients leads to impaired neural circuits and schizophrenia-like symptoms in mice and human cell models.

m6A RNA modification of mHtt intron 1 regulates the generation of Htt1a in Huntington's Disease

This study investigates how m6A RNA modifications in Htt intron 1 regulate the production of the pathogenic Htt1a transcript in Huntington's Disease.

GPC3-Unc5D complex structure and role in cell migration

This study determines the structure of the GPC3-Unc5D complex and shows its role in guiding neuronal and cancer cell migration.