U. Valentin Nägerl

The paper identifies a female-specific microglial redox program that influences susceptibility to obesity by modulating metabolic resilience and mTORC1 signaling.

The paper uses expansion microscopy and cryo-electron tomography to reveal the precise spatial arrangement of AnkG and neurofascin-186 in the axon initial segment's 190-nm periodic structure.

The paper shows how Ten4 switches between self-recognition and Latrophilin binding to guide neuronal migration through exclusive structural interactions.

This study investigates amyloid plaque penetrability and extracellular space rheology in an AD mouse model using imaging techniques, finding heterogeneous diffusivity and dysregulated extracellular matrix around plaques.

The paper shows that dendrites have nanoscale constrictions that create electrical compartments, altering synaptic integration in neurons.

Faser simulates excitation PSFs in STED microscopy to explore imaging performance and beam properties.

This study evaluates how the tilt of a coverslip affects STED and two-photon microscopy image quality and proposes a method to correct the tilt.

This study shows that axon morphology and function are influenced by membrane mechanics, with activity modulating cholesterol levels and affecting conduction velocity.

The paper investigates how chemical fixation with paraformaldehyde affects the microanatomy of mouse brain tissue using super-resolution microscopy.

This paper develops a 3D-STED microscopy method to improve axial resolution for imaging dendritic spines in the hippocampus of living mice, enabling longitudinal studies of neuroanatomical plasticity.

This paper introduces a method to visualize living brain tissue in real-time with high anatomical detail using light microscopy and fluorescence labeling of interstitial fluid.

This study uses computational models and experimental validation to show that astrocyte nano-morphology shapes Ca2+ signaling and that pathological swelling reduces this activity.

This paper demonstrates aberration correction in STED microscopy to improve imaging depth and resolution in living brain tissue.

This study uses SUSHI to visualize astrocytic microstructures and ECS dynamics in live brain tissue, showing remodeling during osmotic stress.

This study shows that LTP induces astroglial withdrawal, increasing glutamate spillover and inter-synaptic communication.

SpineJ is a semi-automatic ImageJ plugin designed to quantify nanoscale dendritic spine morphology in super-resolution microscopy images.

The paper simulates calcium signaling in fine astrocytic processes to show how spatial organization of IP3R channels affects spontaneous activity.