Author

Ana Granat

Illumina (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Erich B. JaegeriD· 2 shared Tiffany TruongiD· 2 shared Ali Moshrefi· 1 shared Andreas SchereriD· 1 shared Aparna Natarajan· 1 shared Arati RaziuddiniD· 1 shared Ashley Walton· 1 shared Baitang NingiD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetics

Erich B. JaegerORCID

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2 papers

Recent·Most cited

Ultra-deep sequencing reveals no evidence of oncogenic mutations or enrichment by ex vivo CRISPR/Cas9 genome editing in human hematopoietic stem and progenitor cells

M. Kyle Cromer, Valentin V. Barsan, Erich B. Jaeger, Mengchi Wang, Jessica P. Hampton, Feng Chen, Drew Kennedy, Irina Khrebtukova, Ana Granat, Tiffany Truong, Matthew Hebden Porteus

The paper uses ultra-deep sequencing to assess oncogenic mutations in human hematopoietic stem and progenitor cells after CRISPR/Cas9 editing, finding no evidence of tumorigenic variants.

bioRxiv · Oct 27, 2021 · PreprintGenetics

Achieving reproducibility and accuracy in cancer mutation detection with whole-genome and whole-exome sequencing

Wenming Xiao, Luyao Ren, Zhong Chen, Li Tai Fang, Yongmei Zhao, Justin Lack, Meijian Guan, Bin Zhu, Erich B. Jaeger, Liz Kerrigan, Thomas M. Blomquist, Tiffany Hung, Marc Sultan, Kenneth B. Idler, Charles Lu, , Leming M. Shi

This study evaluates reproducibility and accuracy of cancer mutation detection using whole-genome and whole-exome sequencing across multiple sequencing centers and bioinformatics pipelines.

Nature Biotechnology · Sep 1, 2021Peer-reviewedGenomics