Author

Arati Raziuddin

Frederick National Laboratory for Cancer ResearchORCID 0000-0001-9361-8691Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Ali Moshrefi· 1 shared Ana Granat· 1 shared Andreas SchereriD· 1 shared Anjali Nandal· 1 shared Aparna Natarajan· 1 shared Ashley Walton· 1 shared Austin T.K. HokeiD· 1 shared Baitang NingiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

Ali Moshrefi

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 19, 2025

In vivo CRISPR screening identifies NF1/RASA1/TP53 co-mutations and downstream MEK signaling as a common key mechanism of sinonasal tumorigenesis

Kenny Vu, Sreenivasulu Gunti, Ramya Viswanathan…·Nyall R. London

This study identifies NF1/RASA1/TP53 co-mutations and MEK signaling as key drivers of sinonasal tumorigenesis through in vivo CRISPR screening and drug response testing.

DOI 10.1101/2025.05.19.654661

mousegenetic perturbation / CRISPR

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GenomicsNature BiotechnologyPeer-reviewedSep 1, 2021

Achieving reproducibility and accuracy in cancer mutation detection with whole-genome and whole-exome sequencing

Wenming Xiao, Luyao Ren, Zhong Chen…·Leming M. Shi

This study evaluates reproducibility and accuracy of cancer mutation detection using whole-genome and whole-exome sequencing across multiple sequencing centers and bioinformatics pipelines.

192 citationstop 1%

humanwhole-genome sequencing

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