Drug and single-cell gene expression integration identifies sensitive and resistant glioblastoma cell populations
Robert K. Suter, Anna M. Jermakowicz, Rithvik Veeramachaneni, Matthew D’Antuono, L.G. Zhang, Rishika Chowdary, Simon Kaeppeli, Madison Sharp, Pravallika Palwai, Vasileios Stathias, Grace Baker, Luz Clarita Ruiz, Winston M. Walters, Maria L. Cepero, Danielle M. Burgenske, , Nagi G. Ayad
The paper integrates single-cell RNA sequencing data with drug response signatures to identify drug-sensitive and resistant glioblastoma cell states and predict synergistic drug combinations.
Nature Communications · Jan 7, 2026Peer-reviewedCancer Biology