Author

Madison Sharp

Georgetown University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Matthew D’AntuonoiD· 2 shared Michael E. IvaniD· 2 shared Nagi G. AyadiD· 2 shared Ricardo J. KomotariD· 2 shared Rishika ChowdaryiD· 2 shared Robert K. SuteriD· 2 shared Alexandre WojcinskiiD· 1 shared Anatol Oleksijew· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Matthew D’AntuonoORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Drug and single-cell gene expression integration identifies sensitive and resistant glioblastoma cell populations

Robert K. Suter, Anna M. Jermakowicz, Rithvik Veeramachaneni, Matthew D’Antuono, L.G. Zhang, Rishika Chowdary, Simon Kaeppeli, Madison Sharp, Pravallika Palwai, Vasileios Stathias, Grace Baker, Luz Clarita Ruiz, Winston M. Walters, Maria L. Cepero, Danielle M. Burgenske, , Nagi G. Ayad

The paper integrates single-cell RNA sequencing data with drug response signatures to identify drug-sensitive and resistant glioblastoma cell states and predict synergistic drug combinations.

Nature Communications · Jan 7, 2026Peer-reviewedCancer Biology

Identification of disease-specific vulnerability states at the single-cell level

Matthew D’Antuono, Madison Sharp, Rishika Chowdary, Michael E. Ivan, Ricardo J. Komotar, Robert K. Suter, Nagi G. Ayad

The paper identifies three single-cell vulnerability states in glioblastoma using transcriptomic data and CRISPR screens, showing differential drug sensitivity and spatial distribution.

bioRxiv · Dec 4, 2024 · PreprintCancer Biology