A novel mutation alters the stability of PapA2 resulting in the complete abrogation of sulfolipids in clinical mycobacterial strains
Vipul Navinchandra Panchal, Nidhi Jatana, Anchal Malik, Bhupesh Taneja, Ravikant Pal, Apoorva Bhatt, Gurdyal Singh Besra, Lipi Thukral, Sarika Chaudhary, Vivek Rao
The paper identifies a mutation in the papA2 gene of Mycobacterium tuberculosis that leads to loss of sulfolipids by disrupting protein stability and structure.
FASEB BioAdvances · Mar 25, 2019Peer-reviewedMolecular Biology