Identification of SLC35A1 as an essential host factor for the transduction of multi-serotype recombinant adeno-associated virus (AAV) vectors
Xiujuan Zhang, Siyuan Hao, Zehua Feng, Kang Ning, Çağla Aksu Küz, Shane McFarlin, Donovan Richart, Fang Cheng, Ander Zhang-Chen, Richenda McFarlane, Ziying Yan, Jianming Qiu
This study identifies SLC35A1 as a host factor essential for rAAV transduction, showing its role in vector nuclear import across multiple AAV serotypes.
mBio · Nov 27, 2024Peer-reviewedMicrobiology