Identification of Human Transferrin Receptor as an Entry Co-receptor for Parvovirus B19 Infection of Human Erythroid Progenitor Cells
Shane McFarlin, Kang Ning, Xiujuan Zhang…·Jianming Qiu
This study identifies human transferrin receptor 1 (hTfR) as a co-receptor for parvovirus B19 (B19V) entry into erythroid progenitor cells, showing that hTfR binding to the viral VP1u protein is critical for viral internalization and replication.