The therapeutic and diagnostic potential of amyloid β oligomers (AβOs) selective antibodies to treat Alzheimer's disease
Kirsten L. Viola, Maira Assunção Bicca, Adrian M. Bebenek, Daniel L. Kranz, Vikas Nandwana, Emily Alexandria Waters, Chad R. Haney, Maxwell Y Lee, Abhay Gupta, Zachary Brahmbhatt, Weijian Huang, Ting-Tung A. Chang, Anderson S. Peck, Clarissa Valdez, Vinayak P. Dravid, William L. Klein
This paper demonstrates that amyloid β oligomers (AβOs) are key drivers of Alzheimer's disease pathology and shows that AβO-selective antibodies can restore memory function and serve as diagnostic tools.
Frontiers in Neuroscience · Jan 3, 2022Peer-reviewedNeuroscience