Vinayak P. Dravid

Ultra-sensitive water contaminant detection with transcription factor interfaced microcantilevers

The paper develops a biosensor using transcription factors and microcantilevers to detect water contaminants with high sensitivity and speed.

Chromatin packing domains persist after RAD21 depletion in 3D.

The paper shows that RAD21 depletion reduces but does not eliminate chromatin packing domains in electron microscopy, suggesting non-cohesin mechanisms largely control 3D structure.

The therapeutic and diagnostic potential of amyloid β oligomers (AβOs) selective antibodies to treat Alzheimer's disease

This paper demonstrates that amyloid β oligomers (AβOs) are key drivers of Alzheimer's disease pathology and shows that AβO-selective antibodies can restore memory function and serve as diagnostic tools.

Statistical Analysis of Three-Dimensional Chromatin Packing Domains Determined by Chromatin Scanning Transmission Electron Microscopy (ChromSTEM)

The paper introduces ChromSTEM, a method for high-resolution 3D imaging of chromatin structure, and finds that chromatin forms well-defined domains around 100 nm in radius with radially decreasing mass-density.

Nanoscale Chromatin Imaging and Analysis (nano-ChIA) platform bridges 4-D chromatin organization with molecular function

The paper introduces a nano-ChIA platform that combines electron tomography and superresolution imaging to study chromatin structure and dynamics at the single-nucleosome level in live cells.

Quantifying Three-dimensional Chromatin Organization Utilizing Scanning Transmission Electron Microscopy: ChromSTEM

The paper introduces ChromSTEM, a method to quantify 3D chromatin organization using electron microscopy, and finds chromatin is densely packed with heterochromatin having higher density than euchromatin.