Phenotypic and Functional Characterization of Oncohistone Mutations in Breast Cancers
Andrea D. Edwards, Yangyang Dai, Siddharth Singh, Micah A. Thornton, Tulip Sunil Nandu, Ralf Kittler, Cristel V. Camacho, Dan Huang, W. Lee Kraus
This study identifies and characterizes 17 high frequency oncohistone mutations in breast cancer that promote cancer-related phenotypes and may act as potential cancer drivers.
bioRxiv · Apr 29, 2025 · PreprintCancer Biology