Tulip Sunil Nandu

The paper maps PARP1 ADP-ribosylated proteomes in breast cancer subtypes, identifying subtype-specific modifications and their functional implications.

The paper examines the molecular effects of varying estradiol doses on estrogen receptor enhancers in breast cancer cells, finding distinct biological outcomes at low versus high doses.

This study shows that macrophage PARP1 depletion disrupts adipose tissue homeostasis by enhancing cell-cell crosstalk, leading to obesity and metabolic dysfunction.

This study identifies and characterizes 17 high frequency oncohistone mutations in breast cancer that promote cancer-related phenotypes and may act as potential cancer drivers.

This study identifies PARP7 as a key regulator of C/EBPβ-dependent adipogenesis and shows it senses nuclear NAD+ levels to control gene expression and lipid production in mammary glands.

This study identifies XCP, a protein from the lncRNA1456, which interacts with PHF8 to regulate gene expression and cancer pathways in breast cancer.

This study shows that relaxin reduces estrogen receptor alpha phosphorylation and alters estrogen-dependent gene expression in myometrial cells.

The paper shows that KAP1 negatively regulates RNA polymerase II elongation kinetics to enhance signal-induced transcription of Immediate Early Genes.