ECM remodeling and spatial cell cycle coordination determine tissue growth kinetics
Anna P. Ainslie, John Robert Davis, John J. Williamson, Ana Ferreira, Alejandro Torres-Sànchez, Andreas Hoppe, Federica Mangione, Matthew B. Smith, Enrique Martı́n-Blanco, Guillaume Salbreux, Nicolas Tapon
The paper shows that tissue growth in Drosophila abdomen stops due to rapid cell cycle arrest, not gradual slowing, and that ECM remodeling is required for expansion.
bioRxiv · Nov 10, 2020 · PreprintDevelopmental Biology