DNA-PK and the TRF2 iDDR inhibit MRN-initiated resection at leading-end telomeres
Logan R. Myler, Beatrice Toia, Cara K. Vaughan, Kaori Takai, Andreea M. Matei, Peng V. Wu, Tanya T. Paull, Titia de Lange, Francisca Lottersberger
The paper shows DNA-PK and TRF2 inhibit MRN resection at blunt telomeres, preventing fusion through alternative end joining.
bioRxiv · Mar 6, 2023 · PreprintMolecular Biology