Author

Kaori Takai

Rockefeller UniversityORCID 0000-0002-2631-8389Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1 Assay:proteomics· 1

Frequent Co-Authors

Titia de LangeiD· 3 shared Alexander J. StuartiD· 1 shared Andreea M. Matei· 1 shared Beatrice ToiaiD· 1 shared Cara K. VaughaniD· 1 shared Ekaterina V. VinogradovaiD· 1 shared Francisca LottersbergeriD· 1 shared Henry SanfordiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCell Biology

Titia de LangeORCID

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3 papers

Recent·Most cited

Cell BiologyMolecular CellPeer-reviewedDec 1, 2025

Attenuation of ATM signaling by ROS delays replicative senescence at physiological oxygen

Alexander J. Stuart, Kaori K. Takai, Railia R. Gabbasova…·Titia de Lange

The paper shows that reduced ATM signaling via ROS at physiological oxygen delays replicative senescence by inhibiting DDR activation.

13 citations

humanDNA methylation

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Molecular BiologybioRxivPreprintMar 6, 2023

DNA-PK and the TRF2 iDDR inhibit MRN-initiated resection at leading-end telomeres

Logan R. Myler, Beatrice Toia, Cara K. Vaughan…·Francisca Lottersberger

The paper shows DNA-PK and TRF2 inhibit MRN resection at blunt telomeres, preventing fusion through alternative end joining.

5 citations

experimental assay

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GenomicsNature CommunicationsPeer-reviewedApr 7, 2021

Structural variant evolution after telomere crisis

Sally M. Dewhurst, Xiaotong Yao, Joel A. Rosiene…·Marcin B. Imielinski

The paper investigates structural variants (SVs) generated during telomere crisis, showing that BFB cycles and chromothripsis can occur in clones that escape telomere crisis.

38 citations

humanwhole-genome sequencing

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