MicrobiologybioRxivPreprint
END nucleases: Antiphage defense systems targeting multiple hypermodified phage genomes
Wearn‐Xin Yee, Yan‐Jiun Lee, Timothy A. Klein…·Joseph Bondy‐Denomy
The paper identifies ENDPaCF1, a novel defense system in Pseudomonas aeruginosa, which targets hypermodified phage DNA through an endonuclease domain fused to an inactive Endonuclease III, revealing its role in antiphage immunity.
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