Extracellular monomeric and aggregated tau efficiently enter human neurons through overlapping but distinct pathways
Lewis Evans, Thomas Wassmer, Graham Mathew Fraser, James C. Smith, Michael S. Perkinton, Andrew Billinton, Frederick J. Livesey
The paper investigates how monomeric and aggregated tau enter human neurons through distinct pathways, identifying dynamin- and actin-dependent mechanisms for monomeric tau and dynamin-dependent clathrin-mediated endocytosis for aggregated tau.
Cell Reports · Mar 1, 2018Peer-reviewedNeuroscience