Author

Andrew Chess

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:ATAC-seq· 1 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

A. Ercument Cicek· 1 shared Aaron Topol· 1 shared Aarti JajooiD· 1 shared Ahituv NadaviD· 1 shared Ahyeon HwangiD· 1 shared Alex A. PolleniD· 1 shared Alex Kozlenkov· 1 shared Alexandre JourdoniD· 1 shared

Activity by Year

2014-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

A. Ercument Cicek

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Author profile →

3 papers

Recent·Most cited

Massively parallel characterization of psychiatric disorder-associated and cell-type-specific regulatory elements in the developing human cortex

Chengyu Deng, Sean Whalen, Marilyn Steyert, Ryan Ziffra, Pawel F. Przytycki, Fumitaka Inoue, Daniela A. Pereira, Davide Capauto, Scott Norton, Flora M. Vaccarino, Alex A. Pollen, Tomasz Jan Nowakowski, Ahituv Nadav, Katherine S. Pollard, Schahram Akbarian, , Alex Kozlenkov

The paper identifies 46,802 enhancers and 164 psychiatric disorder variants with regulatory effects in the developing cortex and organoids using massively parallel reporter assays and deep learning.

Science · May 23, 2024Peer-reviewedGenomics

Gene Expression Elucidates Functional Impact of Polygenic Risk for Schizophrenia

Menachem Fromer, Panos Roussos, Solveig K Sieberts, Jessica S Johnson, David H Kavanagh, Thanneer M Perumal, Douglas M Ruderfer, Edwin C Oh, Aaron Topol, Hardik R Shah, Lambertus L Klei, Robin Kramer, Dalila Pinto, Zeynep H Gumus, A. Ercument Cicek, , Lara M Mangravit

The paper uses gene expression data from schizophrenia cases and controls to show that common variants at 20% of schizophrenia risk loci regulate brain gene expression, with functional impacts on neural progenitor cells and zebrafish neuroanatomy.

bioRxiv · May 9, 2016Genomics

Single molecule-level detection and long read-based phasing of epigenetic variations in bacterial methylomes

John Beaulaurier, Shijia Zhu, Robert Sebra, Xue-Song Zhang, Chaggai Rosenbluh, Gintaras Deikus, Nan Shen, Diana Munera, Matthew K Waldor, Martin Blaser, Andrew Chess, Eric Schadt, Gang Fang

This paper introduces a novel SMRT sequencing framework for single molecule-level detection of DNA methylation and epigenetic phasing in bacterial methylomes, revealing improved resolution and distinct epigenetic heterogeneity.

bioRxiv · Sep 17, 2014Microbiology