Author

Shijia Zhu

Icahn School of Medicine at Mount SinaiPrimary ORCID profile (0000-0002-2368-2361 · 3 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Shijia ZhuiD3 papers · University of Minnesota

Biology Disciplines

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Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:variant calling· 2 Organism:bacteria (other)· 1 Organism:C. elegans· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Gang FangiD· 2 shared Gintaras Deikus· 2 shared Robert SebraiD· 2 shared Aimee SheniD· 1 shared Alex Kim· 1 shared Ali BashiriD· 1 shared Andrew Chess· 1 shared Andrew KasarskisiD· 1 shared

Activity by Year

2014-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersGenomics

Gang FangORCID

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2 papers

Recent·Most cited

Epigenomic and functional characterization of a core DNA methyltransferase in the human pathogen Clostridium difficile

Pedro H. Oliveira, John W. Ribis, Elizabeth M. Garrett, Dominika Trzilova, Alex Kim, Ognjen Sekulović, Edward A. Mead, Theodore Pak, Shijia Zhu, Gintaras Deikus, Marie Touchon, Colleen Beckford, Nathalie E. Zeitouni, Deena Altman, Elizabeth Webster, , Gang Fang

This study characterizes the epigenome of C. difficile and identifies a conserved DNA methyltransferase that impacts sporulation and other biological processes.

bioRxiv · Jul 23, 2019 · PreprintGenomics

Single molecule-level detection and long read-based phasing of epigenetic variations in bacterial methylomes

John Beaulaurier, Shijia Zhu, Robert Sebra, Xue-Song Zhang, Chaggai Rosenbluh, Gintaras Deikus, Nan Shen, Diana Munera, Matthew K Waldor, Martin Blaser, Andrew Chess, Eric Schadt, Gang Fang

This paper introduces a novel SMRT sequencing framework for single molecule-level detection of DNA methylation and epigenetic phasing in bacterial methylomes, revealing improved resolution and distinct epigenetic heterogeneity.

bioRxiv · Sep 17, 2014Microbiology