Author

Andrew G Clark

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Biophysics· 1 Evolutionary Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell type annotation· 2 Organism:Drosophila· 2 Approach:experimental assay· 2 Assay:behavioral assay· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Ananyo Maitra· 1 shared Anthony Simon· 1 shared Benjamin L de Bivort· 1 shared Carlos Pérez-González· 1 shared Cécile Jacques· 1 shared Chelsea Jenney· 1 shared Daniel L Hartl· 1 shared Danijela Matic Vignjevic· 1 shared

Activity by Year

2014-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperBiophysics

Ananyo Maitra

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Viscoelastic relaxation of collagen networks provides a self-generated directional cue during collective migration

Andrew G Clark, Ananyo Maitra, Cécile Jacques, Anthony Simon, Carlos Pérez-González, Xavier Trepat, Raphaël Voituriez, Danijela Matic Vignjevic

The paper shows that cell clusters migrate persistently on collagen networks by generating asymmetric gradients through viscoelastic relaxation, independent of internal polarity.

Nature Materials · Oct 1, 2022Peer-reviewedBiophysics

Integrative modeling of tumor DNA methylation identifies a role for metabolism

Mahya Mehrmohamadi, Lucas Mentch, Andrew G Clark, Jason W Locasale

This study identifies the role of metabolism in DNA methylation variation across tumors using integrative modeling of multi-platform data.

Nature Communications · Dec 14, 2016Peer-reviewedGenomics

Evolution of resistance against CRISPR/Cas9 gene drive

Robert L Unckless, Andrew G Clark, Philipp W Messer

This study shows resistance against CRISPR/Cas9 gene drive will inevitably evolve unless specific conditions are met, and highlights the need for careful modeling before releasing driver constructs.

bioRxiv · Jun 11, 2016Evolutionary Biology

Transcriptome Differences between Alternative Sex Determining Genotypes in the House Fly, Musca domestica

Richard P Meisel, Jeffrey G Scott, Andrew G Clark

The paper compares gene expression profiles between male house flies with different sex-determining genotypes to investigate evolutionary forces driving sex determination pathway turnover.

bioRxiv · Jun 1, 2015Genomics

Behavioral individuality reveals genetic control of phenotypic variability

Julien F Ayroles, Sean M Buchanan, Chelsea Jenney, Kyobi Skutt-Kakaria, Jennifer Grenier, Andrew G Clark, Daniel L Hartl, Benjamin L de Bivort

The paper investigates genetic control of phenotypic variability by analyzing locomotor handedness in Drosophila, finding heritable variability and identifying genes like Ten-a that influence behavioral variability without affecting the mean.

bioRxiv · Sep 12, 2014Genetics