Author

Anthony Simon

Drugs for Neglected Diseases Initiative

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

A. Kenneth MacLeodiD· 1 shared Alpha A. LeeiD· 1 shared Ananyo Maitra· 1 shared Andrew G Clark· 1 shared Andrew Wells· 1 shared Annette von DelftiD· 1 shared Benjamin PerryiD· 1 shared Blake H. BalcombiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Kenneth MacLeodORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Open-science discovery of DNDI-6510, a compound that addresses genotoxic and metabolic liabilities of the COVID Moonshot SARS-CoV-2 Mpro lead inhibitor

Ed Griffen, D. Fearon, Briana Lynn McGovern, L. Koekemoer, Blake H. Balcomb, Tamás Szommer, Gwendolyn Fate, Ralph P. Robinson, Bruce A. Lefker, Shirly Duberstein, Noa Lahav, Stéphanie Braillard, Laura Vangeel, Manon Laporte, Fabienne Burgat Charvillon, , Annette von Delft

This paper describes the optimization of a SARS-CoV-2 Mpro inhibitor to address genotoxic and metabolic liabilities, leading to improved in vivo efficacy and exposure.

bioRxiv · Jun 16, 2025 · PreprintPharmacology & Toxicology

Viscoelastic relaxation of collagen networks provides a self-generated directional cue during collective migration

Andrew G Clark, Ananyo Maitra, Cécile Jacques, Anthony Simon, Carlos Pérez-González, Xavier Trepat, Raphaël Voituriez, Danijela Matic Vignjevic

The paper shows that cell clusters migrate persistently on collagen networks by generating asymmetric gradients through viscoelastic relaxation, independent of internal polarity.

Nature Materials · Oct 1, 2022Peer-reviewedBiophysics