Embryonic Protein NODAL Regulates the Breast Tumour Microenvironment by Reprogramming Cancer-Derived Secretomes
Dylan Dieters-Castator, Paola Marino Dantonio, Matt Piaseczny, Guihua Zhang, Jiahui Liu, Miljan Kuljanin, Stephen Sherman, Michael Jewer, Katherine Quesnel, Eun Young Kang, Martin Köbel, Gabrielle M. Siegers, Andrew Leask, David Hess, Gilles Lajoie, Lynne-Marie Postovit
This study shows NODAL reprograms cancer cell secretomes to influence fibroblast activation and MSC recruitment in breast cancer.
bioRxiv · Jul 9, 2020 · PreprintCancer Biology