Martin Köbel

This study shows that SMARCA4 loss in endometrial cancer leads to cell state chaos, not stemness, causing dedifferentiation through epigenomic dysregulation.

This study improves transcriptome-wide association studies by integrating pleiotropy-guided methods with GWAS data to identify new cancer susceptibility genes.

This study shows NODAL reprograms cancer cell secretomes to influence fibroblast activation and MSC recruitment in breast cancer.

This study combines genome-wide association data from four cancers to identify shared and novel genetic associations and pleiotropic effects.