A genetically encoded bifunctional enzyme mitigates redox imbalance and lipotoxicity via engineered Gro3P-Glycerol shunt
Xingxiu Pan, Subrata Munan, Austin L. Zuckerman, Andrew Pon, Sara Nunes Violante, Justin R. Cross, Hardik Shah, Valentin Cracan
This paper develops a genetically encoded bifunctional enzyme that reduces redox imbalance and lipotoxicity by enhancing Gro3P biosynthesis and glycerol shunt in mammalian cells.
bioRxiv · Jun 2, 2025 · PreprintBioengineering