Genetic lineage tracing identifies intermediate mesoderm as a novel contributor to mammalian kidney lymphatics
Daniyal J. Jafree, Lauren G. Russell, Αθανασία Σταθοπούλου, Christopher J. Rowan, Andrew T White, Charlotte O’Riordan, Maria Kolatsi‐Joannou, Karen L. Price, Sarah M. Ivins, Liam A. Ridge, Catherine Roberts, Jennifer C. Chandler, Laura Wilson, DALE A. MOULDING, Julie A. Siegenthaler, , David Andrew Long
This study identifies two progenitor sources for kidney lymphatics in mice: Tie2 endothelial lineage and Osr1 intermediate mesoderm, showing a dual origin for kidney lymphatic formation.
bioRxiv · Jul 18, 2025 · PreprintDevelopmental Biology