Septin crosstalk with microtubules and actin is regulated by a GSK3-dependent phosphoswitch
Md Noor A. Alam, TrishaJean C Holt, Andrew W. Schaefer, Franklin Mayca Pozo, Sarath Reghunathan, Sarah M Butts, Priyanka Bhakt, Ilona A. Kesisova, Elias T. Spiliotis
This paper identifies GSK3-dependent phosphorylation of SEPT9 as a mechanism regulating its partitioning between actin and microtubules, affecting neuronal polarization.
bioRxiv · May 9, 2026 · PreprintCell Biology