Elias T. Spiliotis

This study shows that Septin9, associated with microtubules, drives actin assembly and apical expansion in epithelial cells during morphogenesis.

This paper identifies GSK3-dependent phosphorylation of SEPT9 as a mechanism regulating its partitioning between actin and microtubules, affecting neuronal polarization.

This study shows septins buffer actomyosin forces to protect the nucleus from mechanical stress during migration and in non-migrating cells, with SEPT9 amplification linked to reduced genomic damage and higher mortality in breast cancer.