Microbial oral-gut translocation in advanced chronic liver disease is linked to exacerbation of intestinal barrier dysfunction and hepatic fibrosis
Shen Jin, Aurélie Cenier, Daniela Wetzel, Bethlehem Arefaine, Mar Moreno‐Gonzalez, Marilena Stamouli, Merianne Mohamad, Mariia Lupatsii, Emilio García Ríos, Sunjae Lee, Ane Zamalloa, Shilpa Chokshi, Adil Mardinoğlu, Saeed Shoaie, Naiara Beraza, , Melanie Schirmer
The paper identifies oral-gut microbial translocation in ACLD patients linked to intestinal barrier dysfunction and hepatic fibrosis, with prtC encoding bacteria as a biomarker.
bioRxiv · Sep 23, 2025 · PreprintMicrobiology