Temporal Transcriptomics Identifies Isoform-specific Trans-regulation by Multiple lncRNAs in Human iPSCs
Mingfeng Liu, Izabela Mamede, Sajad Sofi, Isabela Tiemy Pereira, Vishantie Dostal, Alison R. S. Pashos, Conor McMahon, Aneesh Waikar, George Stephenson, Thomas R. Cech, John L. Rinn
The paper identifies six lncRNAs that regulate gene expression in trans in human iPSCs, revealing isoform-specific effects and a systemic response to doxycycline exposure.
bioRxiv · May 14, 2026 · PreprintGenomics