Isabela Tiemy Pereira

This study identifies attenuated estrogen signaling and NRIP1 as key factors in trophoblast defects in Down syndrome using patient-derived stem cells.

The paper identifies six lncRNAs that regulate gene expression in trans in human iPSCs, revealing isoform-specific effects and a systemic response to doxycycline exposure.

This study identifies CSDC2 as an RBP critical for cardiomyocyte commitment during cardiac differentiation of hiPSCs, showing its loss impairs differentiation and its recovery rescues it.

The paper identifies CARDEL as a long non-coding RNA involved in human cardiac specification and homeostasis through in vitro differentiation and gene expression analysis.

This study investigates the temporal dynamics of lncRNA Firre-mediated epigenetic and transcriptional regulation, showing rapid and persistent effects on gene expression.