Vorinostat (SAHA) alters the skeletal muscle differentiation program
Veronica Sian, Andreas Roos, Andreas Hentschel, Jaakko Sarparanta, Per Harald Jonson, Sérgio Valente, Antonello Mai, Lucia Altucci, Bjarne Udd, Angela Nebbioso, Marco Savarese
This study examines how SAHA affects skeletal muscle differentiation in C2C12 and L6 cells, showing delayed early differentiation and model-dependent changes in gene and protein expression.
bioRxiv · May 30, 2026 · PreprintCell Biology