Jitender S. Saini

Whole Exome Sequencing in dense families suggests genetic pleiotropy amongst Mendelian and complex neuropsychiatric syndromes

This study uses whole exome sequencing in families with multiple affected individuals to identify rare variants in genes associated with both Mendelian and complex neuropsychiatric syndromes.

Sample size requirement for achieving multisite harmonization using structural brain MRI features

This study determines the minimum sample size needed for multisite harmonization using structural brain MRI features and shows how sample size requirements increase with site variability.

Functional Network Connectivity Imprint In Febrile Seizures

This study identifies altered functional connectivity patterns in children with complex febrile seizures compared to simple febrile seizures, correlating these changes with seizure recurrence and duration.

Fibrinogen and Complement Factor H are promising CSF protein biomarker(s) for Parkinson's disease with cognitive impairment- A Proteomics and ELISA based study

Analysis of whole exome sequencing in severe mental illness hints at selection of brain development and immune related genes

The paper analyzes whole exome sequencing data from individuals with severe mental illness to identify genes under positive selection and their biological functions.

Protocol for Magnetic Resonance Imaging Acquisition, Quality Assurance, and Quality Check for the Accelerator Program for Discovery in Brain Disorders using Stem Cells

The paper describes MRI acquisition, quality assurance, and quality check protocols for a longitudinal study on brain disorders using stem cells, showing consistent and reliable data acquisition.

A series of five population-specific Indian brain templates and atlases spanning ages 6 to 60 years

The paper develops and validates age-specific Indian brain templates and atlases for spatial normalization of MRI data across ages 6-60 years.

Adverse childhood experiences in families with multiple members diagnosed to have psychiatric illnesses

The paper examines the relationship between adverse childhood experiences (ACEs) and the age of onset of psychiatric diagnoses in individuals from families with multiple affected members.

Microstructural Abnormalities of Substantia Nigra in Parkinson’s disease: A Neuromelanin Sensitive MRI Atlas Based Study

This paper constructs a probabilistic atlas of the substantia nigra using NMS-MRI and applies it to PD data, finding increased diffusivity but no anisotropy changes in SNc.

Identification and functional characterization of two novel mutations in KCNJ10 and PI4KB in SeSAME syndrome without electrolyte imbalance

The paper identifies two novel mutations in KCNJ10 and PI4KB in SeSAME syndrome patients and shows their functional impact on Kir4.1 channel activity.

Predictive markers for Parkinson’s disease using deep neural nets on neuromelanin sensitive MRI

This paper uses deep neural networks on NMS-MRI to predict Parkinson’s disease with higher accuracy than traditional methods.