Evaluation of toxicological mechanisms of ochratoxin-A in human primary proximal tubule epithelial cells
Anish Mahadeo, Theo K. Bammler, James W. MacDonald, Angela R. Zheng, Catherine K. Yeung, Jonathan Himmelfarb, Edward J. Kelly
This study investigates OTA toxicity in human kidney cells, showing it causes mitochondrial dysfunction, oxidative stress, and reduced energy production, contributing to kidney disease.
bioRxiv · Aug 29, 2025 · PreprintPharmacology & Toxicology