Directed insulin secretion from beta cells occurs at cortical sites devoid of microtubules at the edges of ELKS/LL5β patches
Margret A. Fye, Pranoy Sangowdar, Anissa Jayathilake, P. H. Regan, Guoqiang Gu, Irina Kaverina
The paper shows that insulin secretion from beta cells occurs at specific cortical sites within ELKS/LL5β patches that lack microtubules, suggesting microtubule absence is critical for secretion.
Molecular Biology of the Cell · May 14, 2025Peer-reviewedCell Biology