Cell BiologyMolecular Biology of the CellPeer-reviewed
Directed insulin secretion from beta cells occurs at cortical sites devoid of microtubules at the edges of ELKS/LL5β patches
Margret A. Fye, Pranoy Sangowdar, Anissa Jayathilake…·Irina Kaverina
The paper shows that insulin secretion from beta cells occurs at specific cortical sites within ELKS/LL5β patches that lack microtubules, suggesting microtubule absence is critical for secretion.
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