Molecular BiologybioRxivPreprint
Non-enzymatic RNA Glycation is a Metabolic Sensor of Cellular Stress
Anna Knörlein, Kaila Nishikawa, Naoya Kitamura…·Yael David
This study identifies mRNA glycation by methylglyoxal as a metabolic stress sensor, showing impaired translation and beta-cell dysfunction, which is mitigated by metformin.
DOI 10.64898/2026.05.18.725511