Author

Ann Janssen

Belgian Nuclear Research Centre

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Developmental Biology· 1

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

André Claude Mbouombouo Mfossa· 1 shared Emre EtliogluiD· 1 shared Hanne PuypeiD· 1 shared Jasmine Buset· 1 shared Jéssica Honorato RibeiroiD· 1 shared Lisa BerdeniD· 1 shared Nicholas RajaniD· 1 shared Roel QuintensiD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperDevelopmental Biology

André Claude Mbouombouo Mfossa

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1 paper

Recent·Most cited

A human-specific, concerted repression of microcephaly genes contributes to radiation-induced growth defects in forebrain organoids

Jéssica Honorato Ribeiro, Emre Etlioglu, Jasmine Buset, Ann Janssen, Hanne Puype, Lisa Berden, André Claude Mbouombouo Mfossa, Winnok Harald De Vos, Vanessa Vermeirssen, Sarah Baatout, Nicholas Rajan, Roel Quintens

The paper shows that radiation-induced DNA damage in human forebrain organoids leads to microcephaly through a human-specific p53-E2F4 repression of microcephaly genes.

iScience · Jan 20, 2025Peer-reviewedDevelopmental Biology