E2F1-3 activate Merkel cell polyomavirus early transcription and viral replication
Nicholas J. H. Salisbury, Supriya Patil-Amonkar, Ann Roman, Galloway Da
This study identifies E2F1-3 as activators of MCPyV early transcription and replication through binding to the NCCR, revealing an E2F/LT/RB1 feedback loop that supports viral replication.
bioRxiv · Nov 15, 2025 · PreprintMicrobiology