Mechanistic Plasticity of the RabGEFs Mon1-Ccz1 and Fuzzy-Inturned
Stephan Wilmes, Jesse Tönjes, Jan-Hannes Schäfer, Anna Lürick, Dovile Januliene, Steven Apelt, Daniele Di Iorio, Seraphine Valeska Wegner, Martin Loose, Arne Moeller, Daniel Kümmel
This study compares the structural and functional mechanisms of Mon1-Ccz1 and Fuzzy-Inturned RabGEFs to explain their target specificity and membrane recruitment.
bioRxiv · Mar 27, 2025 · PreprintBiochemistry